Dementia involves changes in the brain involving amyloid beta plaques and tangles. This results in the loss of neurons and their connections. Thus, it affects a person’s ability to remember and think. Here are some medications that will help you treat Dementia and other cognitive diseases.
Medication for Treating Dementia
According to the U.S. Food and Drug Administration, there are some latest treatment therapies to target the underlying disease process of Alzheimer’s disease. Leqembi is the one medication verified to use for treating Alzheimer’s disease like Dementia.
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Leqembi
The authority approved Leqembi as the best medication to treat Dementia on January 6, 2023. The research used to get agreed involved a study of 856 patients with MCI ( mild cognitive impairment) with no presence of amyloid beta plaques. They received Lecanemah for 79 weeks compared to a placebo group. However, PET imaging was used to estimate the beat plaque in some brain regions.
Shortcomings of taking Leqembi
- There are warnings for the use of Leqembi, which are the following:
- Headache
- Confusion
- Vision changes
- Seizures,
- and nausea.
However, Leqembi should only be used in patients with mild cognitive impairment. The Mayo Clinic experts are cautious but hopeful about treatments that can stop or delay the progression of Alzheimer’s.
Future medication to cure Alzheimer’s diseases
Here is the other medication under consideration to treat Alzheimer’s disease. Human trials are now underway. Much evidence shows that a healthy brain is linked to heart and blood vessel health.
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Aduhekm
In June 2021, the FDA approved another medication, Aduhelm, which removes plaques in the brain. The studies are mixed regarding its effectiveness, and insurance coverage is limited.
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Donanemab
Donanemab is an antibody that shows promise and is currently moving into a phase 3 study.
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Saracatineb
Another medication that was initially developed as a possible cancer cure is Saracatineb.
Effects of Dementia
The conditions affecting Dementia are the following:
- high blood pressure,
- heart disease, diabetes,
- and high cholesterol.
Furthermore, studies are being conducted on which blood pressure medications help with Alzheimer’s, molecular level studies, and the life choices that benefit the heart, such as diet and exercise.
Conclusion
These findings will answer which ones affect the brain and in what ways. It is a long process to develop new drugs. It is also challenging for families who are waiting for help. However, Pharmaceutical companies and non-profit foundations are working together to form The Coalition Against Major Diseases. Further, researchers also have worked harder with clinical data exchanges to make data standards. They will share data more readily with thousands of participants to speed up effective therapies.